NEXIUM 20mg/day is a proton pump inhibitor (PPI) that reduces acid production in the stomach. It reduces the amount of acid produced by the stomach. PPIs are used in a number of conditions including:
NEXIUM 20mg/day may also be used for purposes not listed in this medication guide.
This medication should only be used as part of a treatment plan to reduce the likelihood of a patient developing a condition that requires the use of other medications. It is not a substitute for professional medical advice, diagnosis, or treatment.
NEXIUM 20mg/day may cause a variety of symptoms. Some of these symptoms may be serious, some may be mild and some may be mild. Some of these symptoms may be temporary and some may last longer.
If you experience any of these symptoms after taking NEXIUM 20mg/day, seek medical attention immediately.
It is important to note that NEXIUM 20mg/day does not cure the condition. It only helps to reduce acid production and does not cure it. Therefore, if you have any of these symptoms, seek medical help immediately.
You should take this medicine exactly as prescribed by your doctor. The usual recommended dose is 20-40 mg per day.
If you do not understand the dosage and how it works, ask your doctor or pharmacist for advice. It is important to start NEXIUM 20mg/day on the lower dose and workup the dose over time so that any fluctuations in dose and frequency in the medication are not lost. Do not increase your dose, take a different medicine, or change the dosage without your doctor's approval.
The following groups of people may benefit from taking NEXIUM 20mg/day:
People with a history of gastrointestinal conditions, such as ulcers, bleeding or gastrointestinal perforation.
People with a history of acid reflux disease (such as ulcers, bleeding, or perforation in the stomach or intestines).
People with a history of hyperkalaemia (high potassium in the blood).
People with a history of gastric problems, such as gastric ulcers, gastric bypass surgery, or ulcers in the stomach or intestines.
People with a history of hyperprolactinemia (low levels of prolactin).
People with a history of seizures.
People who are pregnant or breastfeeding.
Children and adolescents (aged 12-17 years).
People with a history of stomach ulcers (such as peptic ulcer disease).
People with a history of liver disease.
People with a history of kidney problems.
People with a history of anemia (an abnormal amount of blood protein in the blood).
People with a history of an autoimmune disorder.
People who are taking a diuretic (water pill).
People who have a history of heart attack, heart failure (such as heart attack in the past), and stroke.
People who have ever had a stomach ulcer or a stomach or intestinal blockage.
People who have a history of stomach bleeding.
People with a history of heart problems, such as a history of heart attack.
People who have ever had a stomach ulcer.
People who have ever had a heart attack.
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Lasting relief for frequent heartburn and acid reflux.
Always read the label and follow the directions for use.
Nexium 24HR 20 mg enteric coated tablets for the lasting symptomatic relief of frequent heartburn, acid regurgitation and other symptoms associated with gastro-oesophageal reflux.
Always take this medicine exactly as described in the Consumer Medicine Information leaflet or as your doctor or pharmacist have told you. Check with your doctor or pharmacist if you are not sure. The recommended dose is one tablet a day. - Do not take more than this recommended dose of one tablet (20 mg) a day, even if you don't feel an improvement immediately. - You may need to take Nexium 24HR for a few days before experiencing the full effect. - Nexium 24HR should be taken for at least 7 days and up to 14 days. - Tell your pharmacist or doctor if you do not feel better while taking Nexium 24HR. If symptoms persist or recur within 2 weeks of completing the course, consult your doctor. Further examination may be required.
Always read the label, use only as directed. Tell your pharmacist or doctor if you notice any of the following and they worry you: nausea or vomiting, constipation, diarrhoea, headache, wind, stomach pain, skin rash, itchy skin, dizziness or dry mouth. These side effects are usually mild. Tell your pharmacist or doctor if you are taking any other medicines, including any that you buy without a prescription from your pharmacy, supermarket or health food shop. Some medicines may interfere with Nexium 24HR. Do not take Nexium 24HR if you are pregnant unless your doctor says so. Ask your doctor about the risks and benefits involved. It is not known if it is safe for you to take Nexium 24HR while you are pregnant. It may affect your baby. Do not take Nexium 24HR if you are breastfeeding. Ask your doctor for more information. It is not known if Nexium 24HR is excreted in breastmilk if you are breastfeeding.
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On Tuesday, the U. S. Food and Drug Administration announced that Nexium, the generic name for the antibiotic Protonix, had been pulled from the market because of possible increased side effects associated with the use of the drug.
The FDA’s decision was based on the drug’s association with a rare condition known as QT prolongation, which is an abnormality in the heart that may cause irregular or irregular heartbeat or rhythm.
“This is not a new problem, and the FDA is aware of the risk of QT prolongation, and the FDA is aware of the need for immediate action in the event that it is an emergency,” said FDA spokesman Rick Rayburn. “The FDA continues to be in a position to take steps to minimize the risk.”
QT prolongation is a condition in which the heart’s electrical activity is abnormal. This leads to a prolonged period of heart rate, usually caused by QT prolongation. This condition affects people with various heart conditions. Patients suffering from QT prolongation may experience symptoms such as:
Symptoms may include chest pain that lasts more than a few minutes, fatigue, or shortness of breath, which can be severe.
“As a result of this new trend in using proton pump inhibitors, the FDA is now considering the possibility of a potentially fatal QT prolongation,” said the FDA’s spokesman, Rick Rayburn. “We are committed to ensuring that patients are provided with the necessary information and medical advice when considering the use of these drugs.”
The FDA has also announced that it will continue to monitor patients who develop sudden episodes of QT prolongation. The condition can cause a sudden and severe drop in heart rate which can lead to a heart attack or death. Patients who develop a sudden and severe heart attack are encouraged to seek immediate medical attention if they experience any of these symptoms.
“We are proud to work with our partners at New York’s Almedee Medical Group to develop a new strategy for managing heart health,” said Dr. Steven J. Nissen, MD, chief of cardiology and president of New York’s Almedee Community-based Heart Foundation, which works to promote health and wellness for patients. “We are committed to providing patients with information and support when treating heart disease, and we are confident that patient education and support will help ensure that patients are informed of the risk associated with this potentially fatal condition and those who may benefit from further investigation.”
The FDA has warned that patients who are at increased risk of cardiac disease or risk factors for the condition may need prompt treatment with proton pump inhibitors.
The FDA has also announced that it will continue to monitor patients who develop sudden episodes of heart palpitations (ringing in the heart’s ventricles) and may need emergency treatment if this condition persists.
“The FDA continues to be aware of the potential side effects associated with proton pump inhibitors (PPIs), and the FDA is committed to working with our partners to provide appropriate and timely access to these drugs for patients,” said Nissen.
The FDA is also continuing to monitor patients who develop sudden episodes of heart palpitations (ringing in the heart’s ventricles) and may need emergency treatment if this condition persists.
“As a result of this new trend in using proton pump inhibitors (PPIs), the FDA is now considering the possibility of a potentially fatal QT prolongation,” said Nissen.
For more information and to find out about the FDA’s QT prolongation warning, visit
ReferencesThe following is a statement from the FDA and the U. Food and Drug Administration:
“This sudden and severe heart rhythm abnormality has led to the risk of hospitalization and death for some patients receiving PPIs.
Nexium contains the active ingredient esomeprazole. It belongs to a group of medicines called ‘anti-HIV medicines.
Nexium is used totreat conditions that cause abnormal cell growth, including cancer. Nexium is also used totreat conditions that stimulate the growth of certain types of cancerNexium belongs to a group of medicines called ‘antiviral
Nexium may causeside effectsof the following medicines:
These medicines can increase the growth of certain types of cancer. The use of Nexium may increase the risk of some conditions getting worse.HIV medicines (e.g., Primaveran Drugs, Sustiva)
Nexium may alsoincrease the risk of some conditions getting worseThese include,,, and. You may be more likely to have, an allergic reaction (including,,,,,,,, and ) if you take Nexium if you take it with:
Nexium is not recommended for use by women who are pregnant or breastfeeding. Consult your doctor or pharmacist for more details if you are pregnant or breastfeeding, or for advice about the risks and side effects.
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